A large part of the Top-Up TV service will close this autumn to make way on Freeview for two new television channels from five.
Established and new American television drama, comedy, films, sport and youth programming will be Five US.
Milkshake! Five's pre-school strand will extend to be part of Five life as will drama, films, soaps, popular factual and lifestyle for a female audience.
Chief Executive, Jane Lighting, said: "This is tremendously exciting and the most important development in Five's history since our launch more than nine years ago. We believe these two new channels will play to our programming strengths, highlighting genres in which we have an acknowledged track record. A huge amount of work has gone on behind the scenes to create two propositions that genuinely increase viewer choice across the digital platforms."